It maybe iconic, however, it's a horrible device for pointing from the point of health and ergonomics. And even with all the improvements, I've never seen a mouse handled more accurately than a proper trackball (see Logitech M570). Of course, that depends on the user.
It sounds extreme, by I personally believe that mice destroy the wrists of programmers - that's one of the reasons why we love programs and interfaces with tons of keyboard shortcuts - along with being faster, it's easier on the wrists.
In addition, good keyboard controls can make or break many programs. If you take a look at a program in the adobe suite, you'll normally notice two things. First, that using the program with the mouse generally involves awkward mouse manoeuvrings. However, keyboard shortcuts can eliminate 90% of this.
Third, do you personally recommend using a trackball? I've been experiencing some mild wrist pain lately and am looking for something better than a mouse.