when it comes to commerce it isn't because it makes doing business impossible. How is this practically going to look, Canonical, Red Hat and open source maintainers are going to ship 50 different Linux distributions in the United States?

The reason the US has fairly robust interstate commerce laws is because if you don't you'll have trade barriers between states. Even the most well intentioned internet company can't operate in that ecosystem

Yes the constitution specifically identifies commerce as something Congress has the power to regulate. That doesn't mean states can't have their own rules. Many states have various forms of legalized cannibis, different laws regulating firearms, or automotive emissions.

But this is clearly interstate commerce, given the global nature of the Internet and the distributed nature of development.

I look forward to these laws being shut down in the courts.